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CD178 ANTIGENS
Descriptors Found:
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DeCS
Descriptor
English
:
Fas Ligand Protein
Descriptor
Spanish
:
Proteína Ligando Fas
Descriptor
Portuguese
:
Proteína Ligante Fas
Synonyms
English
:
CD178 Antigen
CD95 Antigen Ligand
CD95 Ligand
CD95L
Fas Ligand
Fas Ligand (FasL)
FasL Protein
TNF Superfamily, Member 6
Antigen, CD178
Antigens, CD178
CD178 Antigens
Tumor Necrosis Factor Ligand Superfamily Member 6
Tree Number:
D12.644.276.374.750.249
D12.776.395.550.312
D12.776.467.374.750.249
D12.776.543.550.312
D23.050.301.264.035.305
D23.101.100.110.305
D23.529.374.750.249
Definition
English
:
A transmembrane protein belonging to the tumor
necrosis
factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated
T-LYMPHOCYTES
and NATURAL KILLER CELLS. It plays an important role in immune
homeostasis
and cell-mediated
toxicity
by binding to the FAS RECEPTOR and triggering
APOPTOSIS.
History Note
English
:
2007(1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52293
Unique Identifier:
D053222
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS